Testosterone Replacement Therapy (TRT) is a treatment designed to address low testosterone levels, or hypogonadism, in men. This hormone is key for male sexual development, muscle and bone health, and general wellbeing. TRT can be administered through various means: injections into the muscle, topical gels and creams, skin patches, subdermal pellets, and, though less common due to liver concerns, oral medications. The therapy aims to normalize testosterone levels, thereby improving symptoms like reduced libido, erectile dysfunction, fatigue, muscle loss, and mood changes.

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Proper diagnosis is critical before commencing TRT, as its symptoms can be similar to other health issues. Ongoing medical supervision is required to tailor the therapy to individual needs and manage any side effects, such as acne, sleep disturbances, increased red blood cells, or heightened cardiovascular risk. TRT is generally unsuitable for men seeking to conceive or those with certain cancers. Decisions about undergoing TRT should be made with a healthcare provider, who can help weigh its potential benefits against the risks.